About Addex Therapeutics Ltd
Addex Therapeutics Ltd is a Swiss biopharmaceutical company specializing in the discovery, development, and commercialization of small-molecule therapeutics for central nervous system (CNS) disorders. The company focuses on innovative treatments targeting G-protein coupled receptors and enzymes.
Key Programs & Research
- Dipraglurant – A treatment for Parkinson’s disease levodopa-induced dyskinesia, dystonia, and post-stroke/TBI recovery.
- ADX71149 – An orally active mGlu2 PAM (metabotropic glutamate receptor subtype 2 positive allosteric modulator) for epilepsy.
- GABAB PAM – Investigated for pain, anxiety, overactive bladder, addiction, and substance use disorder.
Strategic Collaborations
- Janssen Pharmaceuticals Inc. – Partnership for mGlu2 PAM compounds targeting CNS diseases.
- Indivior PLC – Research agreement for GABAB PAM compounds in addiction and CNS disorders.
- The Charcot–Marie–Tooth Association – Evaluating GABAB PAM in preclinical CMT1A models.
Company Background
Founded in 2002 and headquartered in Geneva, Switzerland, the company was previously known as Addex Pharmaceuticals Ltd before rebranding to Addex Therapeutics Ltd.